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abstract When something is abstract, it is hard to understand because it is very difficult to imagine. [1/3 definitions]
acoustics the aspects of a room or space that make sounds easy or difficult to hear (used with a plural verb).
adenoid (usually plural) a mass of tissue that grows behind the nose in the upper part of the throat. When swollen, the adenoids can make breathing difficult.
agency a company or organization that does business in support of other companies or people. An agency helps people do things that are difficult or complicated to do just by themselves. [1/3 definitions]
asthma a disease of the lungs that makes it difficult to breathe. Asthma is often caused by an allergy.
at first If you liked something at first, it means you liked it in the beginning or you liked it the first time that you did it or had it. If something is difficult at first, it means that it was difficult in the beginning. Maybe it got easier later.
awkward difficult to use, deal with, or manage. [1/3 definitions]
bail1 (informal) to help out of a difficult situation (often followed by "out"). [1/3 definitions]
bear1 When you bear something, you live with it even though it is difficult or not fun. [1/5 definitions]
bear up to work through something difficult without giving up; endure.
bind a bad or difficult situation. [1/4 definitions]
block If your little brother blocks the door to the bathroom, he makes it difficult for you to get into the bathroom. If a tree falls and blocks the road, cars can't get through. [1/3 definitions]
brace If you brace yourself, you prepare yourself mentally for some possible shock or disappointment or some very difficult thing you have to face. [1/4 definitions]
burden1 something that is carried or difficult to bear. [2 definitions]
cataract a clouding of the lens of the eye, blocking out light and making it difficult or impossible to see. [1/2 definitions]
challenge an interesting or difficult problem or task. [2/6 definitions]
chore an unpleasant or difficult task. [1/2 definitions]
clumsy difficult to handle or use. [1/3 definitions]
comfort to give relief from a painful or difficult situation; soothe. [1/3 definitions]
complex difficult to understand. [1/2 definitions]
complicate to make more difficult to do or understand.