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Children's Dictionary
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desktop the flat, upper working surface of a desk. [2 definitions]
desktop publishing the creation and preparation of text and graphics for publishing using small computers.
desolate without the things that are necessary or desirable for life. [3 definitions]
despair the complete lack of hope. [2 definitions]
desperate not caring about danger because of great need. [3 definitions]
desperation the feeling or condition of being desperate or without hope.
despise to hate or scorn.
despite in spite of; regardless of.
dessert a sweet food served at the end of a meal.
destination the place to which a person is going or goods or baggage are sent.
destine to assign to or send toward a particular place, end, or purpose. [2 definitions]
destiny that which has happened or must happen to someone because of fate or luck.
destitute having no money or other means of living.
destroy to ruin completely.
destroyer a small, fast warship.
destruction the act of ruining completely or destroying. [2 definitions]
destructive causing complete ruin or destruction.
detach to separate from a whole.
detail a small item; a particular. [3 definitions]
detailed giving a lot of information including small, but often important, pieces of information.
detain to keep from going on; stop or delay. [2 definitions]