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spice any of various edible plant substances with a distinctive aroma or taste, such as pepper or ginger, that are used to flavor or preserve food and drink. [5 definitions]
spicy containing strong spices, as food. [3 definitions]
spider any of various eight-legged invertebrates, related to mites and ticks, that typically spin webs in which to nest and catch their prey.
spike1 an object similar in appearance and function to a nail, but longer and thicker, used to fasten or secure heavy timbers, railroad tracks, or the like. [9 definitions]
spill1 to cause or allow (a liquid or small particles or objects) to flow or fall from a container, esp. unintentionally. [10 definitions]
spill the beans to inadvertently or purposely disclose a secret.
spin to draw out, twist, and wind (fibers), or to make (thread or yarn) by this process. [15 definitions]
spinach a leafy green plant widely cultivated as a vegetable.
spinal of, pertaining to, affecting, or near the spine or spinal cord. [3 definitions]
spinal column in vertebrate animals, the row of vertebrae linked together to form the axis of the skeleton and protect the spinal cord; spine; backbone.
spinal cord the thick cord of nerve tissue that extends through the inner canal of the spinal column from the base of the brain to the end of the spine of any vertebrate animal.
spindle a thin notched rod with tapered ends, on which thread is twisted and wound as it is spun. [9 definitions]
spine the backbone in vertebrates; spinal column. [4 definitions]
spiral a curve that begins from and continues to form a circle around a fixed point and that constantly increases or decreases in distance from it, in either a flat or a three-dimensional plane; coil or helix. [6 definitions]
spire1 a tall, narrow, cone-shaped roof or upward projection on a building or outer wall; steeple; pinnacle. [3 definitions]
spirit the vital force that is thought to be an element of human beings; soul. [11 definitions]
spirit away to remove secretly or mysteriously.
spiritual of or pertaining to that which is not of physical matter or substance; supernatural; incorporeal. [7 definitions]
spit1 to eject saliva or phlegm forcibly from the mouth; expectorate. [7 definitions]
spit2 a thin, pointed rod on which meat is impaled and rotated while broiling or roasting. [3 definitions]
spite the malicious wish to hurt, bother, or humiliate someone. [3 definitions]