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Midwest the north central part of the United States from the Rocky Mountains through Ohio, Kansas, and Missouri; Middle West.
Missouri a river of the central United States. It flows from Montana southeast through several states to Missouri, where it joins the Mississippi River. [1/2 definitions]
Missouri River a major river that flows from the state of Montana mostly southeast until it joins the Mississippi River in Missouri. The Missouri River is considered the longest river in the United States. It is the main tributary of the Mississippi River.
MO an abbreviation for Missouri.
pony express a system of delivering the mail using riders on horseback. The pony express ran between St. Louis, Missouri and Sacramento, California during 1860 and 1861.