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afflict to cause pain or suffering to.
affliction a condition of pain or suffering, or the cause of such a state.
agony great or intense pain and suffering in the mind or body, usually over a long period of time.
alcoholic suffering from alcoholism. [1/2 definitions]
anguish terrible pain or suffering of the mind or body.
catastrophe an event that brings great harm, suffering, or loss to a large area or many people; terrible disaster.
compassion a feeling of sharing another's suffering that leads to a desire to help.
console1 to give comfort in time of loss or suffering; make less sad.
cruel willing to cause pain or suffering; showing no mercy. [2 definitions]
curse something that brings harm or suffering. [1/6 definitions]
dire causing, likely to cause, or involving terror or suffering. [1/2 definitions]
disaster a sudden event causing much damage or suffering. [1/2 definitions]
distress worry, pain, or suffering, or anything that causes suffering. [1/3 definitions]
evil an act, condition, or force that causes suffering or harm. [1/3 definitions]
famished suffering from very great hunger; starved.
hardship a condition of great want, suffering, or difficulty. [1/2 definitions]
hell a condition or place of great pain and suffering. [1/2 definitions]
hurt to cause pain, harm, or suffering to. [3/6 definitions]
mad suffering from rabies. [1/6 definitions]
melancholy suffering from or likely to suffer from sadness or depression. [1/3 definitions]
misery a state of need and suffering caused by being poor, sick, or in trouble. [1/2 definitions]