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an·guish

anguish

 
pronunciation:
aeng gwihsh
features:
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part of speech: noun
definition: terrible pain or suffering of the mind or body.
He felt anguish at not having been able to save the animals from the fire.
synonyms:
agony, grief, torment
antonyms:
bliss, joy
similar words:
distress, misery, pain, sorrow, suffering, torture, woe
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  emotion, sadness